methyl 4-(2-(trimethylsilyl)ethynyl)benzoate
methyl 4-(2-(trimethylsilyl)ethynyl)benzoate
CAS: 75867-41-3
Molecular Formula: C13H16O2Si
methyl 4-(2-(trimethylsilyl)ethynyl)benzoate - Names and Identifiers
methyl 4-(2-(trimethylsilyl)ethynyl)benzoate - Physico-chemical Properties
| Molecular Formula | C13H16O2Si |
| Molar Mass | 232 |
| Storage Condition | 2-8°C |
methyl 4-(2-(trimethylsilyl)ethynyl)benzoate - Upstream Downstream Industry
| Downstream Products | 4-ETHYNYL-BENZOIC ACID 4-(TRIMETHYLSILYLETHYNYL)BENZYL ALCOHOL 4-ETHYNYLBENZYL ALCOHOL 97 CHIR-090 |
methyl 4-(2-(trimethylsilyl)ethynyl)benzoate - Introduction
methyl 4-(2-(trimethylsilyl)ethynyl)benzoate is an organic compound with the formula C13H18O2Si. The following is a description of some properties, uses, preparation methods and safety information of the compound:
Nature:
-Appearance: Colorless or light yellow liquid.
-Solubility: Soluble in organic solvents, such as ethanol, dichloromethane, etc.
-Melting point: About -20 ° C.
-Boiling point: About 230 ° C.
-Density: about 0.97g/cm³.
Use:
- methyl 4-(2-(trimethylsilyl)ethynyl)benzoate is commonly used in chemical reactions in organic synthesis, such as coupling reactions, alkynylation reactions, etc.
-It can also be used as a reagent to introduce alkynyl functional groups in organic synthesis.
Method:
- methyl 4-(2-(trimethylsilyl)ethynyl)benzoate can be synthesized by the following steps:
1.4-Hydroxybenzoic acid methyl ester reacts with chloromethyltrimethylsilane to generate 4-(chloromethylbenzoic acid methyl ester).
2. methyl 4-(chloromethanyl) benzoate is reacted with alkaline copper salts (such as cuprous chloride, cuprous iodide, etc.) and dehydrochlorinated to obtain methyl 4-(2-(trimethylsilyl)ethynyl)benzoate.
Safety Information:
- methyl 4-(2-(trimethylsilyl)ethynyl)benzoate has low toxicity under regular handling.
-When using, should follow the correct personal protective measures, such as wearing chemical protective gloves, goggles and protective clothing.
-Avoid skin contact and inhalation of its vapors. If you accidentally come into contact with the skin or enter the respiratory tract, you should immediately rinse with plenty of water and seek medical help in time.
-It is strictly prohibited to contact with oxidants and high temperature sources to prevent fire or explosion accidents.
-The compound should be stored in a dry, well-ventilated place.
Nature:
-Appearance: Colorless or light yellow liquid.
-Solubility: Soluble in organic solvents, such as ethanol, dichloromethane, etc.
-Melting point: About -20 ° C.
-Boiling point: About 230 ° C.
-Density: about 0.97g/cm³.
Use:
- methyl 4-(2-(trimethylsilyl)ethynyl)benzoate is commonly used in chemical reactions in organic synthesis, such as coupling reactions, alkynylation reactions, etc.
-It can also be used as a reagent to introduce alkynyl functional groups in organic synthesis.
Method:
- methyl 4-(2-(trimethylsilyl)ethynyl)benzoate can be synthesized by the following steps:
1.4-Hydroxybenzoic acid methyl ester reacts with chloromethyltrimethylsilane to generate 4-(chloromethylbenzoic acid methyl ester).
2. methyl 4-(chloromethanyl) benzoate is reacted with alkaline copper salts (such as cuprous chloride, cuprous iodide, etc.) and dehydrochlorinated to obtain methyl 4-(2-(trimethylsilyl)ethynyl)benzoate.
Safety Information:
- methyl 4-(2-(trimethylsilyl)ethynyl)benzoate has low toxicity under regular handling.
-When using, should follow the correct personal protective measures, such as wearing chemical protective gloves, goggles and protective clothing.
-Avoid skin contact and inhalation of its vapors. If you accidentally come into contact with the skin or enter the respiratory tract, you should immediately rinse with plenty of water and seek medical help in time.
-It is strictly prohibited to contact with oxidants and high temperature sources to prevent fire or explosion accidents.
-The compound should be stored in a dry, well-ventilated place.
Last Update：2024-04-10 22:29:15
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Product Name: Methyl4-((trimethylsilyl)ethynyl)benzoate Request for quotationCAS: 75867-41-3
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Product Name: methyl 4-(2-trimethylsilylethynyl)benzoate Visit Supplier Webpage Request for quotationCAS: 75867-41-3
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Mobile: +86-18621343501
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Wechat: 18621343501
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Product Name: methyl 4-(2-(trimethylsilyl)ethynyl)benzoate Visit Supplier Webpage Request for quotation
CAS: 75867-41-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 75867-41-3
Tel: 18301782025
Email: 3008007409@qq.com
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